Declared technologies base

TRANSFER OF INNOVATIONAL TECHNOLOGIES

PROCEDURE FOR THE PROGNOSIS OF THYROID CANCER PROGRESSION RISK


Purpose of the development: Preventive medicine.

Recommended application field: medicine.

Advantages over analogues: Absolute specificity and sensitivity in the determining of the thyroid cancer progression risk.

The development stage readiness: tested in laboratory condition

Technical and economic effect: DNA is amplified using specific methylic and unmethylic primers for p15 gene by Methylation Specific Polymerade Chain Reaction. When it is obtained DNA methylation band they predict risk for cancer development, but when two bands result: one band of methylated and one band of unmethylated DNA - lack of the risc. Patents MD 4038

Description of the development:
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Invention provides identification of the methylation profiles of p15 gene in the DNA extracted from malignant tumor fragment of the thyroid gland and their comparison with the profiles of normal peritumoral tissue.

Information about newness of the development:
there are Ukrainian patents -- 1 items

Possibility of transfer abroad:
Licence's sale
Combinated reduction to industrial level

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Country Moldova

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E-mail: gal@uintei.kiev.ua

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