NOVEL "SMART" OLIGOMETRIC DRUG AND NUCLEIC ACID CARRIERS AND NANOSCALE SYSTEMS OF THEIR TARGETED DELIVERY
Recommended application field:
Medicine. Biotechnology.
The work was performed in cooperation with the Institute of Cell Biology of NASU, wich is co-owner of the
development. The technology of the synthesis is protected by Ukrainian patents, US patent was obtained.
Advantages over analogues:
1. The methods of the obtaining novel carriers and delivery systems provide the purposeful control of the functionality
and molecular weight characteristics of the carriers, colloidal-chemical and rheological properties and ability to
immobilize drugs and DNA.
2. Lower cost in comparison with present analogues.
3. Lover toxicity in comparison with present synthetic analogues.
4. Possibility of the creation of various forms of the medicines for oral, parenteral, transdermal and other methods
of the medicine delivery into body.
5. Possibility of the overcoming natural biological barriers, enhanced efficiency and prolongation
of therapeutic action.
The development stage readiness:
Ready for application
Description of the development:
() In vitro and in vivo novel drug and nucleic acid carriers based on oligoelectrolytes and non ionic oligomers of linear,
block, comb-like and nanogel structures as well as nanoscale systems of their targeted delivery to cells and body have been
created and studied.
New carriers and delivery systems have low toxicity; provide the addressed delivery of the drugs to targeted organ, controlled
release and action prolongation, possibility of the decrease of the anticancer toxis medicine dose as well as overcoming
natural biological barriers in the body.
Laboratory testing and preclinical trial of anticancer medicines on their basis were successfully carried out.
Certif
+
Information about newness of the development:
there are Ukrainian patents -- 2 items there are patents of other countries -- 1 items
corresponds technical description
Ready for implementation
Possibility of transfer abroad:
Licence's sale Licence's sale Technological document's sale Combinated reduction to industrial level
Photo
Country
Ukraine
For additional information turn to: E-mail: gal@uintei.kiev.ua
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