Declared technologies base

TRANSFER OF INNOVATIONAL TECHNOLOGIES

ANTIVIRAL, ANTICANCER AND IMMUNE CORRECTIVE AGENT "IZATIZON"


Purpose of the development: Izatizon - a medicine intended for antiviral, anticancer, antimicrobial and immunocorrective treatment.

Recommended application field: Medicine. Veterinary Medicine.

Advantages over analogues: Izatizon refers to a group of non-toxic substances. Not inhibit hematopoiesis , has no cumulative properties . In applying the inductive phase immunogenesis reduces the manifestations of anaphylactic shock , the property has to increase performance of specific and nonspecific resistance in violation of the immune status . Reduces the muscle tone of the small intestine , increases the sensitivity to acetylcholine and barium chloride . Has antiseptic and anti-inflammatory properties . When applied topically ( spray lubrication of the skin and mucous membranes, bandages, compresses) toxic manifestations and has no irritation . LD 50 by intraperitoneal injection - rats 13,9-45,0 mg / kg in mice - 11,4-32,4 mg / kg, and when enterally - 133,0-319,0 mg / kg and 25,0 -47.0 mg / kg, respectively . 30-day use at doses equal 1/10-1/16 LD-50 caused no complications i pathological changes . In recommended doses izatizon not toxic to animals and humans. Contraindications are not revealed.

The development stage readiness: Introduced in production

Description of the development:
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The integrated product consisting of drugs that have been used and applied as independent agents in medical practice of the former USSR , Ukraine , the Russian Federation and other countries : metisazon ( marboran ) , dimethyl sulfoxide, polietilenglyukol ( twin ) with a molecular weight of 400 . Oily liquid , dark yellow , bitter in taste , with a specific smell. Has no fire and explosion properties. Izatizon recommended for the prevention and treatment of diseases that are caused by viruses and viral- microbial associations. Range of actions includes : herpesviruses , myxoviruses , including influenza A and A- 1 , herpes labiales , herpes zoster , the AIDS virus , Marek's disease , infectious laryngotracheitis , bronchopneumonia horses and calves, and vaccinia virus ektromelii , Venezuelan equine encephalomyelitis virus horse virus enteritis swine enteroviruses waterfowl viruses beneficial insects , plants and fish , as well as micro-organisms : streptococci, staphylococci, pneumococci , tubercle bacillus , pathogenic fungi and yeast , chlamydia and mycoplasma . Izatizon recommended for diseases such etiology : acute respiratory infections ( rhinitis , bronchitis , pneumonia , acute respiratory infections - ARI) , oral disease ( glossitis , gingivitis, stomatitis , periodontitis , periodontal disease ) , skin, and mucous glands (herpes skin and mucous , including the genitals , burns, erysipelas, sores , abscesses , boils , carbuncles , mastitis, limfoadenity ) , cavities ( peritonitis , pleurisy ) , joints (injury , synovitis , arthritis , including nonspecific infectious polyarthritis ), diseases the brain ( meningitis, encephalitis ) , mass infectious viral diseases (influenza , paragrip etc.), premalignant and neoplastic diseases (warts , papillomas , melanoblastoma ) , neuritis and neuralgia , myositis, otitis, sinusitis , prostatitis , fungal skin . Izatizon produced in bottles of 50 , 25 and 10 ml, as well as cylinders for aerosol application. Keep out of the dark place at a temperature of 18-20 ° C. Shelf life of 10 years.

Information about newness of the development:
there are Ukrainian patents -- 1 items

corresponds technical description
Ready for implementation

Possibility of transfer abroad:
Licence's sale
Licence's sale
Technological document's sale
Creation of joint enterprise
Realization of finished commodity

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Country Ukraine

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