Purpose of the development: Measurement of electrical conductivity (capacity) of biological cells and fluids in an alternating in intensity pulsed electric field.

Recommended application field: Cellular Biotechnology, cryobiology, biophysics, biomedicine and health, ecology, monitoring and diagnostics in liquid media technology, physico-chemical studies of liquids, rapid analysis of the quality of liquid foods, etc.

Technical characteristic: Parameters : a series of rectangular voltage pulses with increasing amplitude in the range 0.1-100 V, in increments of 0.1 V ( 400 W , 50 ohm load ); number in a series of 1-25 ; duration in the range of 2-300 ms, with a discrete 2 ms; repetition period within the series range from 1-20 , with increments of 1 . Biotechnical this system can be used , in particular, for the different processes electrical manipulation : electrofusion , stimulation, reversible and irreversible electro breakdowns , etc. whose regimes are determined by the parameters of the conductivity cell in a pulsed field of variable intensity .

Advantages over analogues: Measurement of the conductivity and capacitance of individual biological cells and fluids in the alternating tension on the pulsed electric field, which allows, in particular, in vivo diagnosis and condition of the cell performance of electromagnetic manipulation based on electroporation on a single hardware-based pulse methodical conductometry.

The development stage readiness: tested in laboratory condition

Technical and economic effect: Objective assessment of the quality of biological cells, in vivo. Accomplished by measuring the conductivity cell by non-destructive action of electric field pulses. 25% reduction in costs of reagents, increased technological manipulation of cells, establishing the viability and preserve it for future use and biotechnological processes.

Description of the development:
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Biotechnical system impulsnoi conductimetry is the only complex electronic , optical and mechanical devices. Ingredients: - A device for measuring conductivity ; - Positioners to move microelectrodes , which when measured in sight of an inverted microscope with avtoregulyator temperature table ; - Anti-vibration plate for Jitter microelectrodes and cells in the measurement process . To monitor and video morphological cell dynamics in environments exposed to the field in the microscope built color micro camcorder with access to a computer.

Information about newness of the development:
there are Ukrainian patents -- 9 items
amount of patent in used -- 5 items

corresponds technical description
Ready for implementation

Possibility of transfer abroad:
Licence's sale
Combinated reduction to industrial level
Creation of joint enterprise
Joint production, sale, exploitation

Photo

Country Ukraine

For additional information turn to:
E-mail: gal@uintei.kiev.ua