CANCER AUTOVACCINE (CAV) - NEW SPECIFIC ACTIVE ANTITUMOR AGENT
Recommended application field:
Oncology
Advantages over analogues:
Preparation. CAV is repared from autologous tumor by its processing with products of synthesis of a saprophytic microorganism B.subtilis B-7025.
The proteases and antibiotic contained in a filtrate, cause lysis and complete destruction of tumor cells. Thus, the recognition of membranous antigens is increased. They stimulate activity of effector cells, antitumor immunity, immune answer of macrophages, T- and B- lymphocytes, neutrophils, neutrophils, natural killers.
Absence of living cells and viruses in CAV are guaranteed.
Way of introduction. A single dose at hypodermic injection contains 1.5 mg of protein. The revaccination should be carried out after 1 and 6 months.
The vaccine is not toxis, has no anaphiloctogenic properties, does not give local reactions. As a side effect in some patients the insignificant pyrogenic transitional reaction observed with rise of temperature on 1-2 C which conpletely passes in 8-12 hours.
Combination to other methods of therapy. After radical operatin (eaply stages of disease, the adsence of metastasis) on assignment of the physician an effective utilization CAV without chemo- or radiotherapy is possible. If carrying out courses of chemo- or the radiotherapies is necessary immunotherapy by CAV may be started in 18-21 days after their end.
The development stage readiness:
Introduced in production
Description of the development:
() Mechanism of action.Cancer Autovaccine prevents further development of relapses and metastasis in the patients, who were radically operated concerning various tumors. Has a wide spectrum of action causing activation of immune response: raises cytophagous activity of neutrophils, strengthens their digistig function, stimulates antitumor cytotoxic activity of natural killer cells and T- lyphocytes.
Indications for the use. Secjndary (functional) immunodeficit, depression of cytophagous and cytolitic function. It is recommended as independent immunorecriative agent in the hostoperative period, and also for immunocorrection after postoperative chemotherapy and radiotherapy. CAV renders antitumor effect, improves an acceptability of hard courses chemotherapy and radiotherapy, allows to overcome development of cytopenia. It has antirelapse and antimetastatic action practically at all nosological forms of malignant neoplasms. There are no contraindications to the use of CAV.
corresponds technical description
Guarantees stable results getting
Possibility of transfer abroad:
Licence's sale
Photo
Country
Ukraine
For additional information turn to: E-mail: gal@uintei.kiev.ua
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