Recommended application field: Ultrasonic visualization of visco-elastic propertiesof soft tissues could be used in medicine for health care: - Measurement of hardness and viscosity in local pointsin human body during medical checkup (oncology, different pathology); - Measurement of fluids inclusion in human body; - Measurement of muscle strain during athletes training; - Noninvasive monitiring of ultrasonic thermal tussue destruction in real time.

Advantages over analogues: Ionnovative Aspect and Main Advantages: - unigue algorithm of calibration of ARFI and SWEI methods for simultaneous estimation of visco-elastic modulus of tissues; - nominvasive 2D visualization of elasticity and viscosity properties of soft tissues; - early diagnostics of malignant neoplasm and other pathologies; - real time noninvasive control of temperature de-struction margins of tissues pathological areas by powerfull ultrasound; - real time Doppler tehnology.

The development stage readiness: tested in laboratory condition

Description of the development:
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The improved method of visualisation of soft tissues viscoelasticity is based on ARFI (Acoustic Radiation Force Imaging) and SWEI (Shear Wave Elasticity Imaging) modalities. This method uses generation of local shear deformation of soft tissues with ultrasound radiation force. The proposed approach provides for diagnostics of neoplasms and other pathological conditions of soft tissues on very early stages where standard methods of ultrasound visualization do not work. Ecsperimentally confirmed possibility of determination of pathologies less than 5 mm, while standard methods determine only sizes of 15-20 mm. Moreover, the proposed methods culd be used for control of destruction process of pathological tissues. This was confirmed by studies of visco-elastic properties of soft tissues. Both in phantoms and in samples of soft tissues (in particular, samples of muscles and fragments of cow liver) we've obtained the similar dependences of amplitude of displacement growth at the increase of temperature. Thus, it confirms that the control of amplitudes of displacement of tissue with the help of Doppler method could be used for the temperature control during destruction of pathological tissues by powerful ultrasonic radiation.

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Country Ukraine

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E-mail: gal@uintei.kiev.ua