METHOD OF DETERMINATION OF THE FUNCTIONAL STATE OF THE LIVER AT THE DISADVANTAGES AND THE EXEMPTION OF MELATONIN
Purpose of the development:
To investigate the effect of melatonin deficiency and excess on liver status and the treatment technique using melatonin level indicators.
Recommended application field:
Medical diagnostics.
Advantages over analogues:
Experimental studies in humans were successful, which allowed the introduction of methods in medical institutions.
The development stage readiness:
Ready for application
Description of the development:
() The method is distinguished by a study of the lack and excess of melatonin on the state of the liver during its normal functioning and under conditions of oxidative stress. The initial result is the development of physiologically sound doses of melatonin.
Experimental studies in animals (three series of studies on 81 animals) were conducted, which resulted in the development of recommendations for stabilizing the level of melatonin in the liver. The implementation of these recommendations allowed to improve the functional state of the liver, which was confirmed by the results of control studies. The next step was experimental research in humans, which ended successfully. Work is under way to introduce methods in medical institutions.
corresponds technical description
Ready for implementation
Possibility of transfer abroad:
Combinated reduction to industrial level
Photo
Country
Ukraine
For additional information turn to: E-mail: gal@uintei.kiev.ua
|