Purpose of the development: The development is aimed at solving the problem of the synthesis of new heterocyclic compounds with anticancer activity using computer modeling and effective synthetic approaches from simple available reagents.

Recommended application field: Medicine, pharmaceuticals, chemical and biochemical industries.

Advantages over analogues: The effectiveness of the study lies in the fact that new accessible and cost-effective approaches to organic synthesis have been developed - single-reactor, multicomponent, tandem and domino reactions, which are predominantly re- and stereoselective and often occur under mild conditions. The developed synthetic procedures meet the criteria of "green chemistry" and exclude the use of harsh reaction conditions, cost equipment, complex, lengthy, energy-consuming procedures, solvents and reagents that adversely affect the environment and increase the price of the resulting final product.

The development stage readiness: Ready for application

Description of the development:
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The combinatorial libraries of new heterocyclic thiophene compounds were synthesized, their physicochemical properties were characterized, and samples with anticancer activity were obtained.

Information about newness of the development:
there are Ukrainian patents -- 2 items

corresponds technical description
Ready for implementation

Possibility of transfer abroad:
Combinated reduction to industrial level

Photo

Country Ukraine

For additional information turn to:
E-mail: gal@uintei.kiev.ua